Small molecule ligands for bulged RNA secondary structures.
نویسندگان
چکیده
A class of wedge-shaped small molecules has been designed, synthesized, and shown to bind bulged RNA secondary structures. These minimally cationic ligands exhibit good affinity and selectivity for certain RNA bulges as demonstrated in a fluorescent intercalator displacement assay.
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عنوان ژورنال:
- Organic letters
دوره 11 18 شماره
صفحات -
تاریخ انتشار 2009